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Non caseating granuloma with bilateral Hilar lymphadenopathy is a feature of:

 # Non caseating granuloma with bilateral Hilar lymphadenopathy is a feature of:
A. Histoplasmosis
B. Sarcoidosis
C. Silicosis
D. Tannosis


The correct answer is B. Sarcoidosis.

Sarcoidosis is described as a multisystem granulomatous disease of unknown origin characterized by the formation of uniform, discrete, compact, non-caseating epithelioid granulomas. It is more common in blacks than in whites. Though many investigators have regarded this disease, of unknown etiology, both infective and noninfective agents have been implicated. Currently the infectious etiology is more favored with focus on Mycobacterium and Propionibacterium. It is interesting to note that there was a belief that sarcoidosis is in some way related to tuberculosis. The factors which stood against were inability to culture the bacteria from the pathological tissues and difficulty in identifying them in stained sections.

Reference: Shafer's Textbook of Oral Pathology 7th Edition.

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