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BPKIHS First Year BDS past Question- UNIT 1 - March 2014

21st MAR 2014

B.P. Koirala Institute of Health Sciences, Dharan, Nepal
1st year BDS
Internal Assessment Examination, March 2014
Paper - II A

(GENETICS, GROWTH AND DEVELOPMENT, IMMUNOLOGY & BLOOD)

Time - 2 Hours
 Total Marks: 125
SHORT ANSWER QUESTIONS

SECTION - 'A'

ANATOMY 
1. Classify chromosomal disorders with examples of each.                        5
2. Draw a labeled histological diagram of lymph node.                              5
3. Write the criteria and examples of X-linked recessive disorder.             5


                                                                    SECTION - 'B'
PHYSIOLOGY

4. State Landsteiner's law. Explain Rh and ABO blood group on the basis of this law.      2+2=4
5. With the help of flow diagram, explain the extrinsic pathway in blood coagulation.      4
6. Explain the role of erythropoietin in red blood cells production.       4
7. Draw the general, somatic and neural growth curves and briefly compare their patterns.     4
8. Explain the role of cytotoxic T cell in cellular immunity.              4



SECTION 'C'
BIOCHEMISTRY
9. Define the terms isotypes, idiotypes and allotypes.  Draw a labeled diagram of immunoglobulin.      3+2=5
10. Write similarities and differences between the processes of DNA and RNA synthesis.      5
11. Enumerate different post-translational modifications of polypeptide chain. Explain the function of chaperones.              3+2=5
12. Describe the mechanism of gene regulation with the help of lac operon model.          5
13. Explain how polymerase chain reaction (PCR) helps to amplify a target sequence of DNA.     5
14. Explain with a diagram mechanism of  iron absorption in the intestine.         5


SECTION 'D'
PATHOLOGY
15. Enumerate the types of Hypersensitivity reactions. Give at least two examples for each. Write briefly about type II hypersensitivity reaction.          2+1+2=5
16. Enumerate the types of blood components. What are the immediate and delayed blood transfusion reactions.         2+4 =6
17. Describe the peripheral smear and bone marrow findings of Megaloblastic anemia.     5+3=8
18. Enumerate six differences between AML and ALL.                                                     6
19. Classify Hemolytic Anaemia.                                                                                        5


SECTION 'E' 

MICROBIOLOGY
20. Draw a labeled diagram of HIV.                           5
21. Write short note on innate immunity.                   5
22. List the fungi causing opportunistic infection. Add a note on approach to lab diagnosis of any one of them.       2+3=5 


SECTION 'F'
PHARMACOLOGY
23. Explain warfarin effect in pregnancy.                 5
24. Explain Cyclophosphamide effect in urinary bladder.        5
25. Explain Cyclosporine effect in kidney.                               5


***

MCQs in Oral Pathology - Diseases of Microbial Origin


# Endotoxin is released from:
A. Candida albicans
B. Streptococcus sanguis
C. Gram negative bacteria
D. Actinomyces viscosus

# All of the following oral conditions can give rise to bacteremias, EXCEPT:
A. Extraction of tooth
B. Periodontitis
C. Endodontic therapy
D. Dentinal caries

# The most common extraoral cause of halitosis is:
A. Indigestion
B. Alcohol intake
C. Chronic sinusitis
D. Diabetes mellitus

# The typical triad of maxillary sinusitis are:
A. Nasal congestion, pathological secretion, Headache
B. Nasal congestion, trismus, epiphora
C. Nasal congestion, maxillary tooth pain, bloody discharge from the sinus
D. Nasal obstruction, headache, ear ache

Leutic Glossitis is caused by:

# Leutic glossitis is  an intraoral manifestation caused by:
A. Mycobacterium tuberculosis
B. Actinomycosis
C. Treponema pallidium
D. Streptococcus



The correct answer is C. Treponema pallidium. 

Leutic glossitis or syphilitic glossitis is atrophic or interstitial glossitis due to tongue involvement by treponema. The importance of leutic glossitis is the chance of undergoing malignant transformation.

Advantage of Digital Radiography

# One advantage of digital radiography is:
A. All the teeth can be in a single film
B.  Highly economical
C. The radiographic images are obtained immediately
D. Pulpal vitality can be accurately assessed


The correct answer is: C. The radiographic images are obtained immediately.

Advantages of digital radiography are:
- direct display of the image which is dynamic rather than static
- less patient exposure due to greater sensitivity
- Elimination of the need of darkroom