Unit 1 - Blood - Physiology Past Questions - MBBS / BDS First Year - BPKIHS


1.  Describe briefly the kinetics and life span of leucocytes. Compare and contrast the functions of neutrophils and eosinophils. 2+3=5
2.  Describe the sequence of reactions to mismatched blood transfusion. 5
3.  Explain the genesis of granulocytes and their regulation using flow chart. 5
4.  Explain the anticoagulant mechanisms of endothelium of blood vessel. 5
5.  Describe the role of platelets in hemostasis. 5

1.  Enlist the functions of plasma proteins. Explain any one of them. 2.5+2.5=5
2.  What is cross matching in blood transfusion? Explain its significance. 3+2=5
3.  Define hemostasis and describe about any 3 anti-clotting mechanisms in the body 2+3=5
4.  Explain the different stages of erythropoiesis with a diagram. 5
5.  Differentiate between intrinsic and extrinsic pathways of blood coagulation. 5

1.  What is Rh factor? Explain the consequence of Rh incompatibility in blood transfusion and pregnancy. 1+5=6
2.  Describe the role of endothelium blood vessels in anticlotting mechanism. 4
3.  Describe the cytoskeletal proteins of RBC. List 4 advantages of biconcavity of RBC. 3+2=5
4.  Draw a flow-chart showing stages of erythropoiesis. State the role of erythropoietin on it.  3+2=5
5.  Enlist five functions of plasma proteins. Explain any one of them. 3+2=5

1.  State any four factors regulating erythropoiesis. Explain the most important factor among them. 2+3=5
2.  Enlist any five functions of plasma proteins. Describe any one of them. 2.5+2.5=5
3.  What is cross matching in blood transfusion? Explain its significance. 3+2=5
4.  Explain the intrinsic pathway of blood coagulation with the help of a flow diagram. 5
5.   Explain the role of thrombomodulin and plasminogen in anti-clotting mechanism 2.5+2.5=5

1.  Explain the mechanism of clot dissolution. 5
2.  Mention any four mechanisms that normally prevent coagulation of blood inside the blood  vessels. Describe any one them. 2+3=5
3.  Describe the regulatory role of erythropoietin in red blood cells production. 4
4.  State Landsteiner’s law of blood grouping with examples. 3+2=5
5.  Mention any four functions of plasma proteins. Describe
any two of them. 2+2+2=6

1.  Describe various stages of erythropoiesis with changes that occur during each successive stage. 4+2=6
2.  Briefly describe the fate of hemoglobin breakdown. 5
3.  Describe briefly the mechanism of platelet plug formation. 4
4.  Explain in brief the anti-fibrinolytic mechanisms. 5
5.  Briefly describe Rh incompatibility. 5

1.  Define cytokines. Explain their role in hemopoiesis with flowchart. 1+4=5
2.  Explain the role of endothelium of blood vessels inn anti- clotting mechanism. 5
3.  How circulatory neutrophils invade the offending agents in an area of tissue damage & perform the bactericidal effect? 3+2=5
4.  Describe the consequences of mismatched blood transfusion. 5
5.  Explain the role of erythropoietin in the erythropoiesis. 5

1.   List the major contents of platelets and briefly function. 5
2.  Describe the regulation of erythropoiesis. 5
3.  Describe the erythroblastosis fetalis. 5
4.  Describe the anti-clotting mechanisms. 5
5.  Describe the leucopoiesis. 5

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