# Primary immunoglobulin secreted or activated after vaccination:
A. IgM
B. IgA
C. IgG
D. IgE
The primary immunoglobulin secreted or activated after vaccination is:
C. IgG
Explanation:
IgG is the most abundant antibody in blood and extracellular fluid, making up ~75% of serum immunoglobulins. It is the key effector of the secondary immune response (activated after initial exposure or vaccination).
IgM is produced first during the primary immune response but is short-lived. Vaccination typically aims to induce long-term immunity via IgG.
IgA is important for mucosal immunity (e.g., respiratory/gut lining) but is not the dominant systemic response to vaccines.
IgE is associated with allergies/parasitic infections and plays no significant role in vaccine-induced immunity.
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