Atherosclerosis is due to:

 # Atherosclerosis is due to 

a. HDL receptor defect 

b. apolipoprotein E deficiency 

c. decreased LDL activity 

d. decreased lipoprotein lipase 

The correct answer is B. Apolipoprotein E deficiency.

Apolipoprotein (apo) E is recognized for its unparalleled ability to suppress atherosclerosis .The expression of apoE in the macrophage has long been recognized to suppress atherosclerosis by preventing foam cell formation in the vessel wall.

APOE was initially recognized for its importance in lipoprotein metabolism and cardiovascular disease. Defects in APOE result in familial dysbetalipoproteinemia aka type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron, VLDL and LDL.

An amalgam restoration is considered:

 # An amalgam restoration is considered _____.

A. Primary prevention

B. Secondary prevention

C. Tertiary prevention

D. Both primary and tertiary prevention

The correct answer is B. Secondary prevention.

Secondary prevention is the elimination or reduction of a disease after it occurs. An amalgam restoration is considered secondary prevention because tooth decay is removed and a restoration is placed. 

Amount of fluoride in smear size toothpaste for children age less than 3 years:

 # Amount of fluoride in smear size toothpaste for children age less than 3 years: 

a. 0.1mg 

b. 0.2 mg 

c. 0.5 mg 

d. 1 mg 

The correct answer is A. 0.1 mg.

For children younger than 3 years, caregivers should begin brushing children's teeth as soon as they begin to come into the mouth by using fluoride toothpaste in an amount no more than a smear or the size of a grain of rice. Teeth should be brushed thoroughly twice per day (morning and night) or as directed by a dentist or physician. Children's brushing should be supervised to ensure that they use the appropriate amount of toothpaste.

Source: AAPD recommendation 2021

A person with glaucoma should not receive:

 # A person with glaucoma should not receive: 

a. Sedatives 

b. Vasoconstrictors 

c. Anti-sialogogues 

d. Local anesthetics 

The correct answer is C. Anti-sialogogues.

Antimuscarinic mydriatics like tropicamide, cyclopentolate, etc. produce both mydriasis and cycloplegia, and tend to raise i.o.p. in glaucoma patients. Therefore, antimuscarinics are to be avoided in glaucoma patients.