Listerine is contraindicated in patients taking:

 # Listerine is contraindicated in patients taking:
A. Phenytoin
B. Cyclosporin
C. Nifedipine
D. Disulfiram

The correct answer is D. Disulfiram.

Listerine antiseptic and its generic counterparts are approved by the ADA Council on Dental Therapeutics to help prevent and reduce supragingival plaque and gingivitis. The active ingredients
in Listerine are methyl salicylate and three essential oils (eucalyptol, thymol, and menthol). Listerine has been shown to be effective in reducing plaque and gingivitis compared with placebo rinses in young healthy adults. Listerine may exacerbate xerostomia because of its high alcohol content, ranging from 21.6% to 26.9%. Listerine is generally contraindicated in patients under treatment for alcoholism
who take Antabuse (disulfiram). Listerine may benefit patients who do not tolerate the taste or staining of chlorhexidine and who prefer OTC medicaments that are less expensive and easier to obtain.

Reference: Carranza's Clinical Periodontology, 12th Edition, Page no: 450

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