Skip to main content

Cancer which most commonly metastasizes to jaw bone is:

# Cancer which most commonly metastasizes to jaw bone is:
A. Breast
B. Prostatic
C. Lung
D. Kidney


The correct answer is A. Breast

Metastasis to the jaw bones mainly occurs in the posterior region of the mandible, ramus, and the condyle, which are rich in red bone marrow. Metastasis to the maxilla is rare and comprises one-fifth of all metastatic tumors to the jawbones.[1] The male-to-female ratio is almost equal with a ratio of 1:1.1. The mean age of patients is 45 years.[2] The primary focus in women is usually located in the breasts, reproductive organs, thyroid gland, and kidneys, whereas in men it is in the lungs, prostate, kidneys, bones, large intestine, and suprarenal glands.[3,4,5] Metastases to the jaw bones almost originate from infraclavicular regions. The diffusion through Batson's venous system is the principal process of the oral cavity metastasis.[6] Histologically, the primary foci are usually carcinomas, and among them adenocarcinomas are more common. Adenocarcinoma is usually a metastasis from the breasts in women or from the lungs, alimentary canal, or prostate in men. 


References: 
1. Antunes AA, Antunes AP. Gnathic bone metastasis: A retrospective study of 10 cases. Braz J Otorhinolaryngol. 2008;74:561–5. [PubMed[]

2.  Singh H, Kumar P, Nirwan A, Kaur R. Possible pathogenetic mechanisms and overview of metastatic tumours to the oral cavity. Internet J Oncol 8 []
3. Friedrich RE, Abadi M. Distant metastases and malignant cellular neoplasms encountered in the oral and maxillofacial region: Analysis of 92 patients treated at a single institution. Anticancer Res. 2010;30:1843–8. [PubMed[]
4. Kaugars GE, Svirsky JA. Lung malignancies metastatic to the oral cavity. Oral Surg Oral Med Oral Pathol. 1981;51:179–86. [PubMed[]
5. Shin SJ, Roh JL, Choi SH, Nam SY, Kim SY, Kim SB, et al. Metastatic carcinomas to the oral cavity and oropharynx. Korean J Pathol. 2012;46:266–71. [PMC free article] [PubMed[]
6. Batson OV. The function of the vertebral veins and their role in the spread of metastases. 1940. Clin Orthop Relat Res. 1995:4–9. [PubMed[]



Comments

Popular Posts

Dental MCQs - Multiple Choice Questions in Dentistry

SELECT THE TOPIC YOU WANT TO PRACTICE. # LOK SEWA  AAYOG PAST QUESTIONS Medical Entrance Preparation MCQs # Digestive System and Nutrition MCQs # Reproductive System MCQs # MCQs on Sense Organs # Nervous System MCQs # Cardiovascular System MCQs # Endocrine System MCQs # Assorted Dental MCQs - Part 1 #AIIMS MDS ENTRANCE EXAM YEARWISE COLLECTION *** AIIMS Nov 2001 *** AIIMS Nov 2002 *** AIIMS Nov 2003 *** AIIMS Nov 2004 *** AIIMS Nov 2005 *** AIIMS Nov 2006 *** AIIMS Nov 2007 Part 1 *** AIIMS Nov 2007 Part 2 *** AIIMS Nov 2008  *** AIIMS Nov 2009 *** AIIMS Nov 2010 *** AIIMS Nov 2012 *** AIIMS Nov 2013 *** AIIMS Nov 2014 *** AIIMS Nov 2015 *** AIIMS May 2016 *** AIIMS May 2015 *** AIIMS May 2014 *** AIIMS May 2013 *** AIIMS May 2012 *** AIIMS May 2011 # DENTAL MATERIALS *** Amalgams *** Physical Properties *** Metallurgy *** Impression Materials *** Dental Ceramics and Miscellaneous *** Gypsum Products *** Dental Cements *** Restorative Resin...

Most Important Operative Dentistry MCQs With Explanations

1. The following chemically bond to the tooth: A. Composite resin. B. Dental sealants. C. Glass ionomer cement. *** D. All of the above. 2. Compomer restorative materials are: A. Glass ionomer with polymer components B. Resin systems with fluoride containing glasses. *** C. Composite resin for cervical restorations only. Explanation: The composition of compomers is similar to that of a dental composite however it has been modified, making it a polyacid-modified composite. This results in compomers still requiring a bonding system to bond to tooth tissue. Although the name compomer implies that the material possesses a combination of characteristics of both composite and glass ionomers, these materials are essentially polymer-based composites that have been slightly modified to take advantages of the potential fluoride-releasing behavior of glass ionomers. 3. Loose enamel rods at the gingival floor of a class II amalgam cavity should be removed using : A. Straight chisel...

MCQs in Endodontics - Disinfection and Obturation

# Obturation of a root canal should achieve: A. Tug back B. Hermetic seal C. Fluid free seal D. All of the above # The purpose of a root canal sealer is to: A. seal the tubules of the dentine B. stimulate healing in periapical region C. prevent discoloration D. fill the space between solid core material and pulp canal walls

MCQs every Dentists should Know - MEDICALLY COMPROMISED DENTAL PATIENTS - DENTAL CONSIDERATIONS

# Macrolide antibiotics are usually avoided in asthmatics because: A. it can precipitate asthmatic attack B. it interacts with theophylline C. such patients are usually allergic to penicillins D. such patients show penicillin resistant infections # Anticoagulation therapy should be advised to discontinue before minor or major oral surgical procedures if: A. INR (international normalized ratio) is less than 3.0 B. INR is more than 3.0 C. PT (Prothrombin time) is less than 10 seconds D. PT is in range of 10-15 seconds # Which of the following oral manifestations can be often seen in asthmatics? A. Xerostomia B. Geographic tongue C. Enamel hypoplasia D. Aphthous ulcers # A male patient of 76 yrs is on warfarin therapy and needs emergency extractions of a decayed tooth. Select the appropriate protocol given below. A. Do not stop the warfarin therapy – perform the surgery with local hemostatic agents - a...

MCQs in Endodontics - Diseases of the Pulp and Periradicular Tissues

# The treatment of acute periapical abscess is: A. Endodontic therapy or extraction B. Incision and drainage only C. Pulp capping D. None of the above # Internal resorption in a tooth is seen as: A. Ca(OH)2 pulpotomy B. Replacement resorption C. Non-proliferating lesion D. Desensitizing tooth # The initial pulpal response to any insult is: A. Necrosis B. Ulceration C. Calcification D. Inflammation # Patient reports with severe throbbing pain in relation to mandibular second molar. The tooth is sensitive to both hot and cold food and elicits a painful response on percussion. What would be your treatment of choice? A. Incision and drainage of periapical area B. Endodontic therapy C. Indirect pulp capping D. Partial pulpectomy # The most important aspect of emergency treatment for an acute apical abscess is to: A. Produce sedation B. Obturation C. Establish drainage ...