MCQs on Protein Metabolism - Biochemistry

# Tertiary structure of proteins is maintained by all except:
A. H2 bond
B. Hydrophobic
C. Ionic bond
D. Disulphide bond
E. None of the above

# Which of the following is a derived protein?
A. Protamines
B. Peptones
C. Prolamines
D. Lactalbumin

# Albumins and globulins are __ proteins.
A. Simple
B. Derived
C. Conjugated
D. Structural

# Quaternary structure of protein is:
A. The arrangement sequence of amino acids in the polypeptide chain
B. Inter relation between amino acids in a single polypeptide chain
C. Inter relation of amino acids in 2 polypeptide chains
D. The inter relation and arrangement of polypeptides in a protein with more than 2 polypeptide chains

# Biuret test is confirmatory test for:
A. Protein
B. Fat
C. Carbohydrate
D. None of the above

# Glycine is present in:
A. Hemoglobin
B. Glutathione
C. Purines
D. Creatine
E. All of the above

# Indole ring is present in:
A. Tryptophan
B. Valine
C. Methionine
D. Histidine

# Which of the following amino acid is involved in gluconeogenesis:
A. Glycine
B. Valine
C. Cysteine
D. All

# Amino acid carrier defect is found in:
A. Maple syrup urine disease
B. Alkaptonuria
C. Phenylketonuria
D. Cystinuria

# The following is false about tryptophan:
A. Non essential amino acid
B. Involved in serotonin synthesis
C. Involved in niacin synthesis
D. Involved in melatonin in synthesis

# In maple syrup urine disease the amino acids excreted in the urine are:
A. Leucine
B. Isoleucine
C. Valine
D. All of the above

# Proteins are absorbed from GIT as:
A. Amino acids
B. Peptides
C. Peptones
D. All of the above

# Digestion of proteins is initiated by:
A. Amylase
B. Sucrase
C. Chymotrypsin
D. Pepsin

# Histidine is converted to histamine by:
A. Transamination
B. Hydroxylation
C. Decarboxylation
D. Reduction

# Collagen is rich in:
A. Glutamate and glycine
B. Alanine and glycine
C. Proline and glycine
D. Glutamate and proline

# A mutation that converts an amino acid codon to a stop codon is a:
A. Nonsense mutation
B. Transversion
C. Silent mutation
D. Frame shift mutation

# Which one of the following amino acids is purely ketogenic?
A. Proline
B. Phenylalanine
C. Isoleucine
D. Leucine

# Decarboxylation of which of the following amino acids results in formation of a vasodilator:
A. Valine
B. Arginine
C. Histidine
D. Glutamic acid

# All of the following are globular proteins except:
A. Prolamines
B. Albumin
C. Globulin
D. Myosin

# A small calcium binding protein that modifies the activity of many enzymes and other proteins in response to changes of ca+2 concentration is known as:
A. Cycline
B. Calmodulin
C. Collagen
D. Kinesin

# Albinism is a genetic disease that results in incomplete metabolism of:
A. Histidine
B. Cystine
C. Tyrosine
D. Alanine

# Iron is complexed in haemoglobin to:
A. Leucine
B. Histidine
C. Isoleucine
D. Valine

# Urea is produced by the enzyme:
A. Urease
B. Uricase
C. Arginase
D. Glutaminase

# Creatine is formed metabolically from:
A. Tryptophan
B. Arginine
C. Phenylalanine
D. Histidine

# Urinary protein is detected by:
A. Barfoed test
B. Hay's test
C. Boiling test
D. Ehrlich's test

# Major source of ammonia in the kidney is:
A. Urea
B. Aspartate
C. Glutamine
D. Glutamate

# Which is the byproduct of the urea cycle?
A. Aspartate
B. Succinate
C. Ornithine
D. Fumarate

# Key enzyme in urea synthesis is:
A. Urease
B. Carbamyl synthetase
C. Arginase
D. Ornithine

# Amino acids excreted in the urine in cystinosis:
A. Cystine
B. Ornithine
C. Arginine
D. Lysine
E. All of the above

# Ammonia is detoxified in liver to form:
A. Uric acid
B. Glutamine
C. Creatinine
D. Urea

# Heme in haemoglobin is:
A. Between Helix C and D
B. Surrounded by non polar environment
C. Bonded to E7 histidine
D. Protoporphyrin IX

# At pH 7 the binding of 2,3-DPG to hemoglobin occurs at which site?
A. Sulphydryl group
B. Carboxy terminal
C. Amino terminal
D. Histidine

# Cytochromes are:
A. Pyridine nucleotides
B. Riboflavin containing nucleotides
C. Metal containing flavoproteins
D. Iron-porphyrin proteins

# False statement about haemoglobin structure:
A. Hb has 2 polypeptide chains
B. Iron is present in ferrous state
C. Hb structurally similar to myoglobin
D. Ferrous ions are in porphyrin rings

# Which of the following is a precursor of protoporphyrin?
A. Alanine
B. Leucine
C. Histidine
D. Glycine

# Which of the following is not a part of hemoglobin molecule?
A. Pyrrole rings
B. Vinyl groups
C. Histidine
D. Ferric ions

# The following is not a carrier protein:
A. Ceruloplasmin
B. Transferrin
C. Transcobalamine
D. Haptoglobulin

# In Hartnup's disease __ is excreted in the urine.
A. Ornithine
B. Glutamine
C. Tryptophan
D. Phenylalanine

# Urea is formed in:
A. Brain
B. Kidney
C. Liver
D. Intestine

# Thyroxine and catecholamines are derived from:
A. Tyrosine
B. Tryptophan
C. Alanine
D. Leucine

# "Argentaffinoma" is characterized by excess excretion of:
A. 5- Hydroxy indole acetate
B. 3- Hydroxy phenyl pyruvate
C. Phenyl lactate
D. Phenyl acetate

# Which of the following is not a post transcriptional modification of RNA?
A. Splicing
B. 5' capping
C. 3' polyadenylation
D. Glycosylation

# The primary role of chaperones is to help in:
A. Protein synthesis
B. Protein degradation
C. Protein denaturation
D. Protein folding

# The protein rich in basic amino acids, which functions in the packaging of DNA in chromosomes, is:
A. Histone
B. Collagen
C. Hyaluronic acid binding protein
D. Fibrinogen

# The amino acid residue having an imino side chain is:
A. Lysine
B. Histidine
C. Tyrosine
D. Proline

# The numbers of essential amino acid are:
A. 6
B. 8
C. 12
D. 16

# Most common non protein nitrogenous fraction of blood:
A. Urea
B. Uric acid
C. Urobilinogen
D. Creatinin

# The nitrogen content in 50 gm of a typical dietary protein is most likely to be:
A. 5 gm
B. 8 gm
C. 10 gm
D. 16 gm

# The fastest moving fraction of protein in serum when subjected to paper electrophoresis is:
A. Albumin
B. Alpha 1 Globulin
C. Beta Globulin
D. Gamma Globulin

# The class of amino acids that contains only non essential amino acids is:
A. Acidic
B. Basic
C. Aromatic
D. Branched chain

# The daily requirement of protein for the adults is:
A. 6 gms
B. 60 gms
C. 120 gms
D. 250 gms

# All are true about glutathione EXCEPT:
A. It is a tripeptide
B. It converts hemoglobin to methemoglobin
C. It conjugates xenobiotics
D. It scavenges free radicals and superoxide ions

# Colloidal osmotic pressure of plasma is by:
A. Albumin
B. Fibrinogen
C. Globulin
D. Prothrombin

# Glutamine replaced by valine in sickle cell anaemia is characterized by:
A. Non sense mutation of beta chain
B. Missense mutation of beta chain
C. Degradation of beta chain
D. Deletion of beta chain

# Alkaptonuria an inherited metabolic disorder is due to the deficiency of:
A. Homogentisate oxidase
B. Cystathionase
C. Pheylalanine hydroxylase
D. Tyrosine transaminase

# Mannose 6 phosphate containing freshly synthesized proteins are directed to:
A. Nucleus
B. Lysosomes
C. Mitochondria
D. Golgi apparatus

# In the body, metabolism of 10 g of protein would produce approximately:
A. 1 Kcal
B. 41 Kcal
C. 410 Kcal
D. 4100 Kcal

# All are genetic amino acid deficiency diseases except:
A. Phenylketonuria
B. Alkaptonuria
C. Homocystinuria
D. Galactosemia

# Both ketogenic and glucogenic amino acid is:
A. Isoleucine
B. Leucine
C. Arginine
D. Glycine

# The amino acid which undergoes most significant hepatic oxidative deamination which is used for urea synthesis is:
A. Glutamine
B. Glutamate
C. Aspartate
D. Arginine

# Mucin is a:
A. Nucleoprotein
B. Glycoprotein
C. Phosphoprotein
D. Chromoprotein

# Source of nitrogen in the urea cycle are:
A. Arginine & Ammonia
B. Aspartate & Ammonia
C. Uric acid & Ammonia
D. Glutamate & Ammonia