# Which of the following locations would a perforation demonstrate the BEST prognosis? A. Floor of pulp chamber B. Coronal 1/3 of root C. Middle 1/3 of root D. Apical 1/3 of root The correct answer is D. Apical third of root. Apical perforations occur through the apical foramen or the body of the root to form a new canal. The more apical the perforation, the more favorable the prognosis for the tooth. (except for the coronal perforations)