# "Koplik's spots" are associated with: A. Smallpox (Variola) B. German measles (Rubella) C. Mumps D. (Rubeola) The correct answer is. D. Measles (Rubeola) Before immunization, measles was very common during childhood so that 90% of the population had been infected by age 20. Measles (also called Rubeola) is a highly contagious viral illness characterized by a fever, cough, and a spreading rash. It is caused by a paramyxovirus. The incubation period is 1 to 2 weeks before symptoms generally appear. The oral lesions are pathognomonic of this disease. These characteristic "Koplik's spots" usually occur on the buccal mucosa. They are 1-2 mm, yellow-white necrotic ulcers that are surrounded by a bright red margin. Rubella (or German measles) is a fairly benign viral disease. The symptoms usually include a red, bumpy rash, swollen lymph nodes (most often around the ears and neck), and a mild fever. Some people will feel a little achy. The virus can manifest in th...