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Bleeding joints is a characteristic feature of:

 #  Bleeding joints is a characteristic feature of:
A. Vitamin C deficiency
B. Vitamin K deficiency
C. Hemophilia
D. Thrombocytopenia


The correct answer is C. Hemophilia.

Patients with hemophilia exhibit persistent bleeding, either spontaneous or following even slight trauma that produces the mildest of abrasions or cuts. Hemorrhage into the subcutaneous tissues, internal organs, and joints is also a common feature and may result in massive hematomas.

An asymptomatic tooth has deep caries on occlusal surface. Radiograph shows radiopaque mass at apex of the tooth. This mass is most likely to be:

 # An asymptomatic tooth has deep caries on occlusal surface. Radiograph shows radiopaque mass at apex of the tooth. This  mass is most likely to be:
A. Cementoma
B. Condensing osteitis
C. Chronic apical periodontitis
D. Acute apical periodontitis



The correct answer is B. Condensing osteitis.

In condensing osteitis, radiographs demonstrate radiopacity which is not attached to tooth, entire root outline is visible, lamina dura intact and periodontal ligament is widened. These features differentiate it from cementoblastoma, in which the radiopacity is attached to tooth, lamina dura absent and root outline is not visible. In condensing osteitis the tooth may be vital or non-vital.

In a leukemic patient, bleeding does not stop because:

 # In a leukemic patient, bleeding does not stop because:
A. Decreased platelet count 
B. Increased WBC count
C. Decreased calcium level
D. Decrease in coagulation level


The correct answer is A. Decreased Platelet Count

The sign and symptoms of acute leukemia result from either bone marrow suppression or infiltration
of leukemic cells into organs tissues. These changes cause anemia, thrombocytopenia and a decrease in
neutrophils. Thrombocytopenia causes spontaneous bleeding such as petechiae, ecchymoses, epistaxis,
melena. It may necessary to perform surgery on patients with platelet counts in the range of 25,000
because of the difficulty in achieving platelet levels due to circulating platelet antibodies.


Diamond Blackfan anemia is characterized by:

 # Diamond Blackfan anemia is characterized by:
A. Inherited thrombocytopenia 
B. Inherited leucopenia
C. Erythroid aplasia
D. All of the above


The correct answer is C. Erythroid aplasia.

Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. DBA causes low red blood cell counts (anemia), without substantially affecting the other blood components (the platelets and the white blood cells), which are usually normal. This is in contrast to Shwachman–Bodian–Diamond syndrome, in which the bone marrow defect results primarily in neutropenia, and Fanconi anemia, where all cell lines are affected resulting in pancytopenia.

First noted by Hugh W. Josephs in 1936, the condition is however named for the pediatricians Louis K. Diamond and Kenneth Blackfan, who described congenital hypoplastic anemia in 1938. 



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