Vitamin related to coenzyme A:

 # Vitamin related to coenzyme A:

A. Thiamine

B. Riboflavin

C. Cobalamine

D. Pantothenic acid

The correct answer is D. Pantothenic acid.

• Co-enzyme A is an important component of fatty acid synthase complex. The Co-enzyme A is a complex molecule containing B complex vitamin pantothenic acid and a molecule of beta mercaptoethanol amine. 

• The ACP (acyl carrier protein) also contains pantothenic acid. 

• The important CoA derivatives are: - Acetyl CoA - Succinyl CoA - HMG CoA - Acyl CoA. 

• The functions of Pantothenic acid are exerted through CoA (A for acetylation). It is a component of Pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and Thiokinase. Besides the various functions through coenzyme A, pantothenic acid itself is a component of fatty acid synthase complex and is involved in the formation of fatty acids. 

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Angular cheilosis is frequently associated with the deficiency of:

 # Angular cheilosis is frequently associated with the deficiency of:

A. Thiamine

B. Riboflavin

C. Niacin

D. Folic acid

The correct answer is B. Riboflavin.

Magenta tongue (glossitis), fissures at corners of mouth (cheilosis), are common manifestations of  vitamin B2 deficiency. 

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Lazarine leprosy is a variant of:

 # Lazarine leprosy is a variant of:

A. Lepromatous leprosy

B. Tuberculoid leprosy

C. Intermediate leprosy

D. Dimorphic leprosy

The correct answer is A. Lepromatous leprosy.

Lazarine leprosy: This an unusual type of the disease characterized by ulceration and gangrene. The early lesions are bullae, which soon rupture and become gangrenous. It includes achromic and hypochromic spots of the lepra called lazarine (systematized nervous lepra with leprous erythema, pemphigoid and escharotic), and finally of mixed lepra. 

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Opsonins are:

 # Opsonins are:

A. C3a

B. IgM

C. Carbohydrate binding proteins

D. Selectins

The correct answer is C. Carbohydrate binding proteins.

Opsonins 

• Chemicals causing opsonisation 

• They are specific carbohydrate binding proteins 

Examples of opsonins 

• C3b 

• Fc fragment of antibody or IgG 

• Some serum proteins (like fibrinogen, mannose binding lectin and C reactive protein) 

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