PGCEE MDS 2022: The host modulation therapy that may be used as adjunctive therapy for aggressive periodontitis is

 # The host modulation therapy that may be used as adjunctive therapy for aggressive periodontitis is:

a) Clindamycin

b) Metronidazole

c) Doxycycline

d) Ciprofloxacin

The correct answer is C. Doxycycline.

Host Modulatory Therapy (HMT) is a treatment concept that aims to reduce tissue destruction and stabilize or even regenerate the periodontium. Doxycycline hyclate is available as a 20mg capsule for use by patients twice daily. The mechanism of action is by suppression of the activity of collagenase, particularly that produced by PMNs. NSAIDs inhibit the formation of prostaglandins, including prostaglandin (PGE2). PGE2 is found to upregulate bone resorption by osteoclasts. Flurbiprofen, an NSAID, significantly inhibits radiographic alveolar bone loss compared to a placebo. A recent study suggested that concomitant administration of doxycycline and flurbiprofen may result in

enhancement of the anti collagenase effects of doxycycline. 

Subantimicrobial-dose doxycycline (SDD) may help to prevent the destruction of the periodontal attachment by controlling the activation of matrix metalloproteinases, primarily collagenase and gelatinase, from both infiltrating cells and resident cells of the periodontium, primarily the neutrophils.

PGCEE MDS 2022: Preventive and therapeutic measures for dealing with the periodontal problems during fixed appliance therapy

 # Which of the following are typical and acceptable preventive and therapeutic measures for dealing with the periodontal problems during fixed appliance therapy?

a) Elimination of gingivitis prior to placing orthodontic appliances

b) Home care instruction regarding the use of the toothbrush and water pik during orthodontic treatment

c) Megavitamin therapy

d) Scaling and curettage immediately after appliance removal

The correct answer is A. Elimination of gingivitis prior to placing orthodontic appliances

Maintaining oral hygiene becomes more challenging once the fixed orthodontic brackets are placed. Pre-existing gingivitis should be treated and eliminated before placing the brackets. 

PGCEE MDS 2022: The common site for necrotizing sialometaplasia:

 # The common site for necrotizing sialometaplasia:

a) cheeks 

b) dorsum of tongue

c) palate 

d) gingival

The correct answer is C. Palate.

Necrotising sialometaplasia is a benign, inflammatory reaction of salivary gland that mimics a salivary gland malignancy. Etiology is mostly due to local ischemia. Most common intraoral site is palate followed by buccal mucosa and the type of necrosis is coagulative necrosis. Similar type of lesions in skin are called as syringometaplasia. 

PGCEE MDS 2022: The preferred gingival finish line for veneer is:

 # The preferred gingival finish line for veneer is:

a) Shoulder 

b) Chamfer

c) Shoulder with bevel 

d) Radial shoulder

The correct answer is B. Chamfer.

The preferred gingival finish line for veneer metal restorations is the chamfer. This finish line has been

shown experimentally to exhibit the least stress, so the cement underlying it will have less likelihood of failure. It can be cut with the tip of a round-end diamond while the axial reduction is being done with the side of that instrument.