FIGLU excretion test is used to estimate deficiency of:

 # FIGLU excretion test is used to estimate deficiency of:

A. Vitamin K

B. Vitamin B12

C. Vitamin Folic acid

D. Niacin

The correct answer is C. Vitamin Folic acid.

Folic acid is associated with the metabolism of histidine. Formiminoglutamate (FIGLU) formed in histidine metabolism accumulates and is excreted in urine. Histidine load test utilizing the excretion of FIGLU in urine is used to assess folic acid deficiency. 

Which of the following vitamins is destroyed by heat?

 # Which of the following vitamins is destroyed by heat?

A. Vitamin A

B. Vitamin D

C. Biotin

D. Thiamin

The correct answer is C. Biotin.

Biotin is present in many foods, including liver, grains, and eggs. It is also synthesized by intestinal bacteria. The conversion to a coenzyme simply requires that it be covalently linked to the appropriate enzymes. Biotin acts as a carrier of "activated carboxyl" groups for three key enzymes that catalyze carboxylation reactions. The enzymes and the pathways they participate in are: Pyruvate carboxylase (gluconeogenesis), acetyl-CoA carboxylase (fatty acid synthesis), and propionyl-CoA carboxylase (branched chain amino acid catabolism). Biotin deficiency is rare. Excessive consumption of raw egg impairs biotin absorption due to the presence of a biotin-binding protein, avidin, in egg whites. Antibiotics that alter the intestinal flora can also lead to biotin deficiency. Symptoms of deficiency include alopecia, skin and bowel inflammation, and muscle pain. 

AIIMS MAY 2011 MDS ENTRANCE EXAM PAST QUESTIONS

# All of the cranial nerve have parasympathetic outflow EXCEPT:
A. 5th Nerve
B. 7th Nerve
C. 3rd Nerve
D. 9th Nerve

# The future TMJ shows development at:
A. 12 week
B. 10 week
C. 18 week
D. 16 week

# Area that lies immediately lateral to the anterior perforating substance is:
A. Orbital gyrus
B. Uncus
C. Optic chiasma
D. Limen insulae

 

# Which of the following organ is located posterior to pancreas?
A. Kidney
B. Stomach
C. Colon
D. Duodenum

# Intrinsic factor of Castle is secreted by which of the following cells in Gastric glands?
A. Chief cells
B. Parietal cells
C. Mucus cells
D. B cells

# A patient was diagnosed with isolated increase in LDL. His father and brother had the same disease with increased cholesterol. The likely diagnosis is:
A. LDL receptor mutation
B. Familial lipoprotein lipase deficiency type I
C. Familial type 3 hyperlipoproteinemia
D. Genetic defect in LDL receptors

During a Le fort I maxillary osteotomy, the tooth most likely to be injured by a low osteotomy line is the:

 # During a Le fort I maxillary osteotomy, the tooth most likely to be injured by a low osteotomy line is the:

A. Central incisor

B. Cuspid

C. First bicuspid

D. Lateral incisor

The correct answer is B. Cuspid.

The cuspids, or canine teeth, have the longest roots in both the maxilla and mandible. The average length of a cuspid tooth from the tip of the root to the tip of the crown is 27 mm. It is vital to know the length and position of the dental roots to avoid injuring the apices of the cuspid teeth during Le Fort I osteotomy and placement of internal fixation (interosseous miniplates or microplates and screws). The dentition may also be injured during stabilization of maxillary or mandibular fractures. The bicuspid, central and lateral incisor, and molar teeth all have roots that are shorter than the roots of the cuspid teeth; the average length of a molar tooth from the tip of the root to the tip of the crown, for example, is 24 mm. Consequently, these teeth are much less likely to be injured during LeFort I osteotomy.