The most anterior point of the upper lip is called the:

  # The most anterior point of the upper lip is called the: 

A. Labrale superius

B. Subnasale

C. Stomion superius

D. Soft tissue nasion

The correct answer is A. Labrale superius.

Labrale superius is the most anterior point of the upper lip. 

B is incorrect: The subnasale is the soft tissue point where the curvature of the upper lip connects to the floor of the nose. 

C is incorrect: The stomion superius is the most inferior point of the upper lip. 

D is incorrect: The soft tissue nasion is the concave point of soft tissue outline at the bridge of the nose. 

Aspirin produces all of the following effects EXCEPT:

  # Aspirin produces all of the following effects EXCEPT:

A. Frank gastric bleeding

B. Prolonged prothrombin time

C. Platelet dysfunction

D. Constipation

The correct answer is D. Constipation.

Adverse effects of aspirin 

• Increased blood loss due to antiplatelet activity 

• Hypersensitivity and idiosyncrasy 

• Salt and water retention 

• Reye's syndrome- a rare form of hepatic encephalopathy seen in children having viral infection (influenza virus) 

Hypothalamic nucleus mainly involved in the secretion of ADH is:

  # Hypothalamic nucleus mainly involved in the secretion of ADH is:

A. Preoptic

B. Supraoptic

C. Paraventricular

D. Suprachiasmatic

The correct answer is B. Supraoptic.

The human pituitary gland consists essentially of two parts both controlled by the hypothalamus. The glandular part is the adenohypophysis or anterior lobe and the neural part is the neurohypophysis or posterior lobe. Both the supraoptic and paraventricular nuclei exert control over both the hormones ADH and oxytocin. But in specific ADH is secreted mainly by supraoptic nucleus of hypothalamus and oxytocin mainly by paraventricular nucleus. From hypothalamus, these hormones are transported to posterior pituitary through hypothalamic- hypophyseal tract by axonal flow. 

# The pathological state that alters the volume of distribution of many drugs is:

  # The pathological state that alters the volume of distribution of many drugs is:

A. Septicemia

B. Duodenal ulcers

C. Congestive heart failure

D. Hypertension

The correct answer is C. Congestive heart failure.

In congestive heart failure the volume distribution is often decreased by 40% and loading doses of drugs should be appropriately reduced. Drug clearance may also be diminished due to decreased blood flow to the liver and kidneys.