According to Contemporary Oral and Maxillofacial Surgery, 6th Edition, the PRINCIPLES OF THERAPY OF ODONTOGENIC INFECTIONS are: Principle 1: Determine Severity of Infection Principle 2: Evaluate State of Patient’s Host Defense Mechanisms Compromised Host Defense States: Uncontrolled Metabolic Diseases • Poorly controlled diabetes • Alcoholism • Malnutrition • End-stage renal disease Immune System–Suppressing Diseases • Human immunodeficiency virus/acquired immunodeficiency syndrome • Lymphomas and leukemias • Other malignancies • Congenital and acquired immunologic diseases Immunosuppressive Therapies • Cancer chemotherapy • Corticosteroids • Organ transplantation Principle 3: Determine Whether Patient Should Be Treated by General Dentist or Oral-Maxillofacial Surgeon Criteria for Referral to an Oral-Maxillofacial Surgeon • Difficulty breathing • Difficulty swallowing • Dehydration • Moderate to severe trismus (interincisal opening less than 20 mm) • Swelling ext...