MCQs on Hematology and Endocrinology Part 1 - General Medicine MCQs

The correct answers are highlighted in green.

# In thrombocytopenic purpura there is: (AIPG-93, 98)
a) Increase in platelet count
b) Decrease in platelet count
c) Normal platelet count
d) Defective platelet function

# Bleeding time is prolonged in: (AIPG-98)
a) Factor VIII deficiency
b) Christmas factor deficiency
c) Von Willebrand disease
d) Vitamin K deficiency

# Which of the following coagulation factors is deficient in classical haemophilia? (AIPG-94)
a) VIII
b) IX
c) X
d) XII


# Aplastic anaemia is: (AIPG-2000)
a) Normocytic normochromic with thrombocytopenia
b) Megaloblasts
c) Hypochromic microcytic
d) Hyperchromic macrocytic

# To assure surgical hemostasis, the best blood product administered preoperatively to patients with classic hemophilia is: (AIPG-92, AIIMS-94)
a) Whole blood
b) Factor 8 concentrate
c) Fresh frozen plasma
d) Factor 9 concentrate

#  In Henoch Scholien purpura there is all except: (AIPG-99)
a) Abdominal pain with proteinurea
b) Acute arthritis
c) Rectal bleeding
d) More common in adults

# Which laboratory test is most useful for patient under dicumarol therapy? (AIIMS-92)
a) PT
b) Platelet count
c) BT
d) CT

#  Macrocytic anaemia is due to deficiency of: (TNPSC-99)
a) Vit B1
b) Vit B12
c) Vit B2
d) Vit B6

#  Drug of choice in chronic lymphatic leukemia is: (TNPSC-99)
a) Busulphan
b) Vincristine
c) Chlorambucil
d) Mercaptopurine

# Prothrombin time is prolonged in all of the following except: (TNPSC-99)
a) Liver disease
b) Disseminated intravascular coagulation
c) Warfarin therapy
d) Von-Willebrand's disease

# WBC count of more than 1,00,000 cells/cc of blood indicates: (AIPG-92)
a) Leukopenia
b) Leukoplakia
c) Leukocytosis
d) Leukemia

# The red blood cells in beta thalassemia are typically:
a) Macrocytic and normochromic
b) Microcytic and hypochromic
c) Normocytic and hypochromic
d) Normocytic and normochromic

# Children of parents with blood group combinations erythroblastosis fetalis:  (AIPG-97)
a) Rh+ father and Rh+ mother
b) Rh+ father and Rh- mother
c) Rh- father and Rh+ mother
d) Rh- father and Rh- mother



# Anemia, splenomegaly, structural defects are seen in: (AIPG-97)
a) Thalassemia major
b) Thalassemia minor
c) Mediterranean anemia
d) Polycythemia

# The condition in which patient present with normal leucocyte count or less than normal and shows WBC in the peripheral blood: (AIPG-99, 02)
a) Aleukemic leukemia
b) Subleukemic leukemia
c) Acute leukemia
d) Chronic leukemia

# A child underwent a tonsillectomy at 6 years of age with no complications. He underwent a preoperative screening for bleeding at the age of 12 years before an elective laparotomy, and was found to have a prolonged partial thromboplastin time but normal prothrombin time. There was no family history of bleeding. The patient is likely to have acquired Vitamin K deficiency: (AIIMS-04)
a) Acquired Vitamin K deficiency
b) Acquired liver disease
c) Factor XII deficiency
d) Mild hemophilia A

# Raised serum alkaline phosphatase is seen in all except: (AIIMS-94)
a) Pagets disease
b) Multiple myeloma
c) Osteomalacia
d) Hyperthyroidism

# Which of the following is true about insulin dependent diabetes mellitus?
a) Insulin dependent diabetes is more common than non-insulin dependent diabetes
b) Insulin dependent diabetes is less common in young age groups compared to non-insulin diabetes
c) Non-ketotic coma is more common in insulin dependent diabetes
d) Insulin dependent diabetes is an autoimmune disorder

# Diabetes mellitus is characterized by: (MAN-98)
a) Polyuria
b) Polydipsia
c) Hyperglycemia
d) All of the above

# Splenomegaly and reticulocytosis are typically absent in which type of anaemia: (KAR-98)
a) G-6 PD deficiency anaemia
b) Myeloblastic anaemia
c) Iron deficiency anaemia
d) Aplastic anaemia

# The most important aspect in treating Disseminated Intravascular Coagulation (DIC) is to: (COMEDK-04)
a) Administer heparin
b) Administer platelets
c) Treat the underlying disease process
d) Achieve normal levels of fibrinogen



# Which of the following is not seen on hemoglobin electrophorens in sickle cell anemia:
a) HbA
b) HbF
c) HbA2
d) HbS



# Which of the following regarding insulin therapy is correct: (MAN-01)
a) Insulin resistance is generally due to an allergic reaction
b) Insoluble neutral insulin is used for the treatment of diabetic ketoacidosis
c) Insulin promotes the passage of potassium with glucose
d) Bipolar insulin is a mixture of isophane and protamine

# The insulin indicated in diabetic ketoacidosis is: (MAN-01)
a) Lento insulin S.C.
b) Soluble insulin S.C.
c) Protamine zinc insulin I.M.
d) Soluble insulin I.V. infusion

#  In poliomyelitis which part of spinal canal is involved: (AIPG-2000)
a) Anterior horn
b) Lateral horn
c) Posterior horn
d) Medial horn

# 17-alpha-hydroxylase deficiency affects the release of: (AIPG-02)
a) Aldosterone
b) Growth hormone
c) Glucocorticoids
d) ACTH

# Addison’s disease is associated with: (AIPG-97)
a) Low blood pressure and oral pigmentation
b) Oral sores
c) Thyrotoxicosis
d) Keratosis  

# Which of the following factors determines whether a patient develops acromegaly or gigantism? (AIPG-98)
a) Sex
b) Age at onset of the tumor
c) Amount of available calcium
d) Degree of function of the tumor

#  In rheumatoid arthritis there is inflammation of: (AIIMS-96)
a) Cartilage
b) Synovial membrane
c) Sclerosis of joints
d) Articular bone

#  A diabetic patient in the waiting room develops giddiness, sweating and confusion. He is suffering from: (MAN-2000)
a) Hypertension
b) Ketoacidosis
c) Hypoglycemia
d) Non-ketoacidosis

# Acetone breath is a feature of: (AIIMS-98)
a) Liver disease
b) Sinusitis
c) Renal disease
d) Diabetes mellitus

# In Grave's disease: (AIPG-95)
a) Exophthalmos is due to proliferation of tissue behind the eye ball
b) Overactive thyroid is in nervous patients only
c) Adenoma of pituitary is there
d) CHF can occur

# Following are sulphonyl urea compounds except: (KAR-01)
a) Tolbutamide
b) Chloropropamide
c) Metformin
d) Glibenclamide

#  Presence of glucose in urine indicates: (AIIMS-99)
a) Patient suffers from diabetes insipidus
b) Patient has consumed excess sugar over long years
c) Renal threshold for glucose is exceeded
d) None of the above

# Renal osteodystrophy differs from nutritional and metabolic rickets due to the presence of: (AIPG-02)
a) Hyperphosphatemia
b) Hypercalcemia
c) Hypophosphatemia
d) Hypocalcemia

# Hyperparathyroidism is associated with: (AIIMS-89)
a) Renal stones
b) Bone resorption
c) Increased level of serum calcium
d) All of the above

# Addison's disease is due to: (AIIMS-96)
a) Hemorrhage in adrenal cortex
b) Basophilic adenoma of pituitary
c) Secondary syphilis
d) Hemorrhage in adrenal medulla

# Which of the following is/are common cause or causes of hyperparathyroidism? (AIPG-94)
a) Carcinoma of parathyroid glands
b) Hyperplasia of parathyroid glands
c) Adenoma of parathyroid glands
d) All of the above

# In Conn's disease, there is an excess of: (AIPG-94)
a) Adrenaline
b) Aldosterone
c) Cortisol
d) Noradrenaline

# Hepatitis B occurs after an incubation period of: (AIIMS-96)
a) 1 week
b) 3 weeks
c) 3 months
d) 6 months

# Osteoporosis is not seen in: (AIPG-99)
a) Thyrotoxicosis
b) Rheumatoid arthritis
c) Post menopausal women
d) None of the above

# Complications of diabetes are:
a) Neuropathy
b) Nephropathy
c) Arthropathy
d) All of the above

# All of the following are the known causes of osteoporosis except: (AIPG-06)
a) Fluorosis
b) Hypogonadism
c) Hyperthyroidism
d) Hyperparathyroidism

# Glucose tolerance test is usually done to assess: (COMEDK-06)
a) Acute pancreatitis
b) Carcinoma of head of pancreas
c) Acinar function of the pancreas
d) Endocrine dysfunction of pancreas

# The gold standard for the diagnosis of osteoporosis is: (AIPG-05)
a) Dual energy x-ray absorptiometry
b) Single energy x-ray absorptiometry
c) Ultrasound
d) Quantitative computed tomography

# An adult patient weighing 70 kg has fasting blood sugar 180 mg/dl. Patient is having? (AIPG-2012)
a) Ketoacidosis
b) Hypoglycemia
c) Hyperglycemia
d) Thyroidism

# Addison's disease is due to: (AIIMS-94)
a) Hypofunction of the pitutary gland
b) Excess of the adrenal medulla
c) Excess of liver enzymes
d) Chronic insufficiency of the adrenal cortex

# Adrenocorticosteroids in excess may cause: (AIIMS-96)
a) Osteoporosis
b) Osteosclerosis
c) Osteochondritis
d) None of the above

# Diminution in normal size of the body, well-proportioned body, fine sparse hair on the head and other hairy regions wrinkled atrophic skin and often hypogonadism could be diagnosed as suffering from: (AIIMS-04)
a) Hypothyroidism
b) Hypopituitarism
c) Hyperthyroidism
d) None of the above




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