Oxygen Dissociation Curve

# At higher CO2 concentration, oxygen dissociation curve of hemoglobin will:
A. Move to left
B. Move to right
C. Become irregular
D. Move upwardly

The correct answer is B. Move to right

Right shift of the curve (decreased affinity of Hb for Oxygen) is caused by the following factors:
- High PCO2
- Low blood pH
- High body temperature
- Increased level of 2,3 DPG (Diphosphorylglycerate or biphosphoglycerate)

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