Pyruvate dehydrogenase complex contains all EXCEPT:

 # Pyruvate dehydrogenase complex contains all EXCEPT:
A. Biotin
B. NAD
C. FAD
D. Co-A


The correct answer is A. Biotin.

Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation. Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the glycolysis metabolic pathway to the citric acid cycle. Pyruvate decarboxylation is also known as the "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate.

The enzymes involved in PDC are Pyruvate dehydrogenase (E1), Dihydrolipoyl transacetylase (E2), and Dihydrolipoyl dehydrogenase (E3). The cofactors involved are: TPP (thiamine pyrophosphate), magnesium, lipoate, coenzyme A, FAD and NAD+. 

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