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MCQs on General Biochemistry

The correct answers are highlighted in green.

# Detoxification of drugs is controlled by:
a) Cytochrome
b) Cytochrome P450
c) Cytochrome C
d) Cytochrome A

# In cytochrome P450, P stands for:
a) Structural proteins
b) Substrate protein
c) Pigment
d) Polymer

# Detoxification or protective synthesis occurs by:
a) Oxidation
b) Reduction
c) Conjugation
d) Any of the above


# The major driving force for formation of membrane lipid bilayer is:
a) Hydrogen bonding
b) Hydrophobic interactions
c) Vander waal forces
d) Not known


# Normal blood pH is :
a) 6.8-7.0
b) 7.0 - 7.12
c) 7.38 - 7.4
d) 7.7 - 8.0

# The most important buffer in RBC is:
a) O2 Hb +Na hemoglobinate
b) O2 Hb +K hemoglobinate
c) HCO3 +KHCO3
d) H2CO3 +NaHCO3

# In ECF main electrolyte is:
a) Na+
b) K+
c) Cl-
d) Proteins  

# Most important compensatory mechanism in metabolic acidosis:
a) Hyperventilation
b) Increased NH3 excretion by kidneys
c) Increased urinary phosphates
d) Increased HCO3 production

# Which of these organelle functions as the digestive system of the cell? (COMEDK-07)
a) Golgi apparatus
b) Mitochondria
c) Lysosomes
d) Rough endoplasmic reticulum

# Cell membrane consists of: (AIIMS-94)
a) Lipids and proteins
b) Lipids only 
c) Protein only
d) None of them

# Rate limiting step in adrenaline synthesis is conversion of:
a) Dopa to dopamine
b) Phenylalanine to tyrosine
c) Tyrosine to dopa
d) Dopamine to nor epinephrine

# A balanced diet consists of: (MAN-2K)
a) 20% proteins, 35% fats , 45% carbohydrates
b) 25% proteins, 25% fats , 50% carbohydrates
c) 20% proteins, 25% fats , 50% carbohydrates
d) 35% proteins , 15% fats , 50% carbohydrates

# Nor epinephrine is converted to epinephrine by:
a) O-methylation
b) Dopa decarboxylase
c) Dopamine hydroxylase
d) N-methylation

# Golgi bodies function as: (AIIMS-97)
a) Protein lipid synthesis
b) Protein synthesis
c) None of them
d) Sorting of glycoproteins

# Ubiquitin is involved in:
a) Electron transport chain
b) Protein folding
c) Intracellular proteolysis
d) Transport of ATP 

# Which of the following is inclusion of cytoplasm? (AIIMS-06)
a) Golgi Body
b) Glycogen
c) Endoplasmic reticulum
d) Ribosome

# Bile acids are formed from:
a) Lipoproteins
b) Amino acids
c) Bilirubin
d) Cholesterol

# Which of the following is a function of the Golgi apparatus? (COMEDK-07)
a) Protein storage
b) t RNA synthesis
c) m RNA synthesis
d) Modification of proteins

# The amino acid required for the synthesis of haem is: (COMEDK -2013)
a) Lysine
b) Glycine
c) Glutamic acid
d) Glutamine

# The most abundant protein present in body is: (AIPG-07)
a) Collagen
b) Hemoglobin
c) Albumin
d) Globulin


# The immediate precursor of norepinephrine is:
a) Phenylalanine
b) Epinephrine
c) Dopamine
d) Tyrosine

# Calcitonin is antagonist:
a) Thyroxine
b) Triiodothyronine
c) Parathyroid hormone
d) Serotonin

# Ribosomes are usually associated WITH: (TNPSC-99)
a) Endoplasmic reticulum
b) Mitochondria
c) Plasma membrane
d) Nucleolus

# During phagocytosis the metabolic process called respiratory burst involves activation of: (AIPG-10)
a) Hydrolase
b) Dehydrogenase
c) Peroxidase
d) Oxidase

# Which of the following has a ketogenic effect on liver?
a) GH
b) Glucagon
c) Androgen
d) Insulin

# The precursor of testosterone is:
a) Methyl testosterone
b) Aldosterone
c) Estrogen
d) Pregnenolone

 # Which of the organelles contain DNA? (PGI-02, AIPG-94)
a) Golgi apparatus
b) Nucleus
c) Nucleolus
d) Ribosomes

# During phagocytosis the metabolic process called respiratory burst involves activation of: (AIPG-10)
a) Hydrolase
b) Dehydrogenase
c) Peroxidase
d) Oxidase



# Bile contains:
a) Cholic acid
b) Chenodeoxycholic acid
c) Lithocholic acid & Deoxycholic acid
d) All of them

# Which one of the following is not a second messenger?
a) Phosphatidyl glycerol
b) cAMP
c) Phosphatidyl inositol
d) cGMP

# Normal blood bilirubin level is:
a) 3 - 4 mg%
b) 0.5 - 1 mg%
c) 1 - 3 mg%
d) 4 - 5.5 mg%

# Which cell organelle contains DNA? (AIPG-03)
a) Mitochondrion
b) Endoplasmic reticulum
c) Golgi body
d) Centriole

# Synthesis of protein occurs on:
a) Nucleus
b) Mitochondria
c) Golgi bodies
d) Poly ribosomes

# Which of the following is precursor of adrenaline and thyroxine synthesis?
a) None of options
b) Tyrosine
c) Tryptophan
d) Phenyl alanine

# Which one of the following human tissues contains the greatest amount of body glycogen? (COMEDK-05)
a) Liver
b) Cardiac muscle
c) Skeletal muscle
d) Kidney

# Bilirubin is produced from:
a) Gall bladder
b) Myoglobin
c) Haemoglobin & Myoglobin
d) Haemoglobin

# Which one of the following human tissues contains the greatest amount of body glycogen? (COMEDK-05)
a) Liver
b) Cardiac muscle
c) Skeletal muscle
d) Kidney

# Oligosaccharide is : (AP-06)
a) Maltose
b) Dextrin
c) Fructose
d) Glucose



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