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# Of the following local anesthetics, which has intrinsic vasoconstrictive action? (MAN -97)

# Of the following local anesthetics, which has intrinsic vasoconstrictive action? (MAN -97)
a) Cocaine
b) Procaine
c) Xylocaine
d) Bupivacaine


The correct answer is : A. Cocaine

All local anaesthetics except cocaine are synthetic compounds and they are vasodilating in nature. Cocaine is a natural local anaesthetic agent and causes local vasoconstriction.

 (Cocaine increases the vasoconstrictive action of adrenaline. If LA with adrenaline is given risk of death is more in cocaine abusers. So they are known as  'walking time bombs.'


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