Which is a premalignant lesion?

 # Which is a premalignant lesion?

A. Oral submucous fibrosis

B. Syphilitic glossitis

C. Erythroplakia

D. Lichen planus

The correct answer is C. Erythroplakia.

Premalignant lesion according to WHO (1978) is defined as a morphologically altered tissue in which cancer is more likely to occur than its apparently normal counterpart. Examples include leukoplakia, erythroplakia, carcinoma in situ. 

Precancerous condition is a generalised state associated with a significantly increased risk of cancer. These include siderophenic dysphagia, submucous fibrosis, lichen planus, syphilitic glossitis.