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A young patient has white thickening of buccal mucosa since birth and it also occurs in nose and esophagus. Most likely diagnosis is:

 # A young patient has white thickening of buccal mucosa since birth and it also occurs in nose and esophagus. Most likely diagnosis is: 
a. accumulation of fordyces granules 
b. chronic hyperplastic candidiasis 
c. white sponge nevus 
d. porokeratosis 



The correct answer is C. White sponge nevus. 

This mucosal abnormality is congenital in many instances. In other cases, it does not appear until
infancy, childhood, or even adolescence, by which time it has generally reached the full extent of its severity. The oral lesions may be widespread, often involving the cheeks, palate, gingiva, floor of the mouth, and portions of the tongue. The mucosa appears thickened and folded or corrugated with a soft or spongy texture and a peculiar white opalescent hue. There is sometimes a minimal amount of folding present. Ragged white areas may also be present which can be removed sometimes by gentle rubbing without any ensuing bleeding. 

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