SEARCH:

Multiple Endocrine Neoplasia (MEN) Syndrome - Types

Multiple Endocrine Neoplasia (MEN) Syndrome
MEN - I
  • Hyperplasia of  pituitary gland with acromegaly
  • Hyperplasia of parathyroid and adrenal cortex
  • Hyperplasia of pancreatic islets with increased production of gastrin, insulin, and glucagon with peptic ulcers and gastric hypersecretion
MEN - II (Sipple's Syndrome)
  • Hyperplasia of parathyroid gland
  • No tumors of pancreas. No peptic ulcer.
  • Patients may have pheochromocytomas of the adrenal medulla and medullary carcinoma of the thyroid gland
MEN - III
  • Pheochromocytomas and Medullary carcinoma of the thyroid gland
  • Oral neuromas that are common on lips, tongue and buccal mucosa.
  • The lips are described as Bumpy lips.


Multiple Endocrine Neoplasia or MEN Syndrome are classified  into following types :
A. MEN - I
  • Hyperplasia of  pituitary gland with acromegaly
  • Hyperplasia of parathyroid and adrenal cortex
  • Hyperplasia of pancreatic islets with increased production of gastrin, insulin, and glucagon with peptic ulcers and gastric hypersecretion
B. MEN - II
  • Hyperplasia of parathyroid gland
  • No tumors of pancreas. No peptic ulcer.
  • Patients may have pheochromocytomas of the adrenal medulla and medullary carcinoma of the thyroid gland
C. MEN - III
  • Pheochromocytomas and Medullary carcinoma of the thyroid gland
  • Oral neuromas that are common on lips, tongue and buccal mucosa.
  • The lips are described as Bumpy lips.

See All Posts / Archives: