A stone present in salivary duct leads to:

 # A stone present in salivary duct leads to:
A. Hyperplasia of salivary gland
B. Hyperplasia of salivary duct
C. Dysplasia of salivary gland
D. Metaplasia of salivary duct

The correct answer is D. Metaplasia of salivary duct.

The duct associated with sialolithiasis exhibits squamous, oncocytic or mucus cell metaplasia.
- Periductal inflammation may also be seen. 
Sialolith is most common in submandibular glands. The main composition of sialoliths found in salivary glands is Calcium phosphate - 75%.

The higher rate of sialolith formation (80-90% of cases) occur in submandibular gland due to:
- Tortuous course of Wharton's duct.
- Higher calcium and phosphate levels
- The saliva from this gland is secreted into oral cavity through ducts against gravity that make them more prone to stasis

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