Golden period for treatment of open wound is?

# Golden period for treatment of open wound is? 

A. 2 hrs 

B. 4 hrs

C. 6 hrs 

D. 8 hrs 

The correct answer is B. 4 hours.

In the first 4 hours after a breach in an epithelial surface and underlying connective tissues, there is delay in the mobilisation of host defences. This period is called 'decisive period' and during this period bacterial colonisation and established infection can begin. It is logical that prophylactic antibiotics will be most effective during this time.