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Crepitus will be seen in the tissues surrounding an infection by:

 # Crepitus will be seen in the tissues surrounding an infection by:
A. Staphylococcus
B. Streptococcus
C. Clostridium tetani
D. Clostridium perfringes



The correct answer is D. Clostridium perfringes. 

■ Clostridium perfringens causes gas gangrene or myonecrosis. 
■ Gas gangrene is characterized by skin colour change from pallor to bronze/purple discoloration and the skin is tense and exquisitely tender. 
■ Gas in the tissues may be obvious with crepitus on clinical examination or visible on radiograph. 
■ Surgical debridement, antibiotic therapy with high-dose I.V penicillin, clindamycin and metronidazole and hyperbaric oxygen therapy are used for treating gas gangrene [Note: Hyperbaric oxygen therapy is also used for osteoradionecrosis and chronic osteomyelitis]. 
■ Cl. tetani causes tetanus and cl. difficile causes pseudomembranous colitis. 



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