Which dentofacial morphology is generally considered the highest risk factor for the development or exacerbation of Obstructive Sleep Apnea (OSA) in adults?

 # Which dentofacial morphology is generally considered the highest risk factor for the development or exacerbation of Obstructive Sleep Apnea (OSA) in adults?

A. Deep Bite Class II Division 2 with an average mandibular plane angle

B. High Angle Class II with marked Mandibular Retrognathia

C. High Angle Class III with Anterior Crossbite

D. Low Angle Class I with severe dental crowding

B. High Angle Class II with marked Mandibular Retrognathia

High-angle Class II malocclusion, characterized by a steep mandibular plane angle (indicating a vertical growth pattern) and significant mandibular retrognathia (receded lower jaw), is a major anatomical risk factor for OSA in adults. This morphology reduces pharyngeal airway space by positioning the hyoid bone and tongue base posteriorly, promoting airway collapse during sleep—exacerbated by the dolichofacial pattern's narrower transverse dimensions. Studies confirm this combination correlates with decreased upper airway volume and higher OSA severity compared to other skeletal patterns. In contrast, Class II Division 2 (A) often features a lower or average angle with less retrognathia impact; high-angle Class III (C) typically widens the airway via mandibular prognathism, offering protection; and low-angle Class I (D) with crowding presents minimal skeletal compromise to airway patency.