MCQs in Pharmacology : General and local anesthetic agents

1. The immobility produced by by general anesthetics in response to painful surgical stimuli is primarily due to their action on:

Motor cortex
Basal ganglia
Thalamus
Spinal cord

2. The minimal alveolar concentration(MAC) of an inhalational anesthetic is the measure of its:
Potency
Therapeutic index
Diffusibility
Oil:water partition coefficient

3. Which of the following is a sign of deep anesthesia?
appearance of tears in eyes
resistance to passive inflation of lungs
fall in blood pressure
Patient makes swallowing movements

4.In which of the following stages of anesthesia, surgical operation should not be performed?

Stage I
Stage II
Stage III, plane 1
StageIII, plane 3

5. Which of the following gases exert 'Second gas effect’ when coadministered with halothane ?
Nitrous oxide
Cyclopropane
Nitrogen
Helium

6. The minimal alveolar concentration (MAC) of halothane is:

75%
25%
7.5%
0.75%

7. The general anesthetic having significant cardiodepressant activity is:
Halothane
Enflurane
Ether
Nitrous oxide

8. Which of the following anesthetics causes malignant hypothermia as its rare complication?
Halothane
Ketamine
Thiopentone sodium
Ether

9. Which of the following is used mainly for the induction of general anesthesia?
Fentanyl + Droperidol
Ketamine
Thiopentone sodium
All of the above

10. Residual CNS depression is least marked after the administration of following anesthetic:
Diazepam
Thiopentone sodium
Lorazepam
Propofol