# Renin secretion is stimulated by all EXCEPT: A. Cardiac failure B. Low Na+ in proximal tubule C. Sympathetic stimulation D. High Na+ in proximal tubule The correct answer is D. High Na+ in proximal tubule. Explanation: Renin secretion, primarily by the juxtaglomerular cells in the kidneys, is stimulated by factors that signal a need to increase blood pressure or sodium retention. These include: A. Cardiac failure: Reduced cardiac output lowers renal perfusion, stimulating renin release to activate the renin-angiotensin-aldosterone system (RAAS) to restore blood pressure. B. Low Na+ in proximal tubule: Detected by the macula densa, low sodium levels signal reduced filtrate delivery, triggering renin secretion to promote sodium reabsorption and increase blood volume. C. Sympathetic stimulation: Activation of the sympathetic nervous system, via beta-adrenergic receptors, directly stimulates renin release to address stress or low blood pressure. D. High Na+ in proximal tubule, however, d...