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Perineural invasion in head and neck cancer is most commonly seen in: PGCEE MDS 2022

 # Perineural invasion in head and neck cancer is most commonly seen in:
a) Adenocarcinoma 
b) Cylindroma
c) Basal cell adenoma 
d) Squamous cell carcinoma


The correct answer is B. Cylindroma.

Adenoid cystic carcinoma (Cylindroma): 
The basal cells are arranged in anastomosing cords or a duct-like pattern, the central portion of may
contain a mucoid material , producing the typical cibriform or Swiss cheese or honey comb pattern. Peri neural spread of tumor cells is seen.

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