MCQs on Oral Manifestations of Systemic Diseases

# Delayed eruption of at least part of the dentition is a recognized feature of all of the following EXCEPT:
A. Rickets
B. Congenital Hyperthyroidism
C. Cleidocranial Dysplasia
D. Cherubism

# A five year old child presents with chronic bed wetting and bilateral loose deciduous first molars. His mother says that he wants to drink water several times during each night. Which of the following is the most likely diagnosis?
A. Hand-Schuller-Christian Disease
B. Marble bone Disease
C. Niemann Pick Disease
D. Polyostotic Fibrous Dysplasia

# Which of the following is related to an enzyme deficiency and involves periodontal destruction around primary teeth?
A. Hypophosphatasia
B. Cyclic Neutropenia
C. Juvenile Periodontitis
D. Papillon-Lefevre Syndrome

# Osteomalacia is:
A. defective osteoid + normal mineralization
B. normal osteoid + defective mineralization
C. abnormal osteoid + abnormal mineralization
D. normal osteoid and demineralization

# The deficiency of which of the following vitamins does not affect tooth development ?
A. Vit- A
B. Vit - D
C. Vit - K
D. Vit - C

# Which of the following tooth structure during formation is most affected due to vit A deficiency ?
A. Enamel
B. Dentin
C. Cementum
D. Periodontal Ligament

# Addison's disease is related to:
A. Adrenal medulla
B. Adrenal Cortex
C. Posterior pituitary
D. Parathyroid gland

# Which of the following is least affected in vitamin C deficiency?
A. Gingival fibres
B. Periodontal ligament
C. Blood vessels of the gingiva
D. Epithelial lining of the mucosa

# Dinesh, a 24 year old male, complains of loose teeth in a single quadrant. His radiograph shows irregular bone loss and histopathology reveals eosinophils and histiocytes. The most probable diagnosis is:
A. Hand Schuller Christian Disease
B. Paget's Disease
C. Osteoclastoma
D. Albright's Syndrome

# A progressive increase in mandibular length and in mandibular interdental spacing in an adult patient is charactersitic of :
A. Periodontosis
B. Hypothyroidism
C. Hyperpituitarism
D. Hypoadrenalism

# Which of the following deficiencies are associated with the disorders of hyperplasia of salivary gland and keratinisation of the salivary gland ?
A. Vit A
B. Vit B
C. Vit C
D. Vit K

# Deficiency of which of the following will cause enamel hypoplasia?
A. Vitamin B and C
B. Vitamin A,C and D
C. Calcium
D. Vitamin C

# Which of the following may be a feature of Acromegaly ?
A. Large tongue
B. Micrognathia
C. Hypoglycemia
D. Crowded teeth

# Gingiva is most commonly affected by the deficiency of :
A.Vitamin A
B. Vitamin B
C. Vitamin C
D. Vitamin D

# Magenta tongue and cracks at corner of mouth are seen in deficiency of:
A. Vitamin B1
B. Niacin
C. Riboflavin
D. Pantothenic acid

# Diabetes insipidus, bone lesions and exophthalmos is seen in:
A. Sickle cell anemia
B. Niemann Pick Disease
C. Littere-Siewe Disease
D. Hand-Schuller-Christian Disease

# The histiocytosis X is a spectrum of disorders, which include the following condition:
A. Eosinophilic granuloma
B. Hand-Schuller-Christian Disease
C. Letterer-Siewe Disease
D. All of the above

# An etiological factor for macroglossia is :
A. Atrophic glossitis
B. Oral Submucous Fibrosis
C. Syphilitic glossitis
D. Hurler's Syndrome

# A disease which only affects the formation and eruption of tooth but does not cause hypoplasia is:
A. Hypoparathyroidism
B. Hyperthyroidism
C. Rickets
D. Syphilis

# Premature exfoliation of deciduous teeth is seen in:
A. Hypophosphatasia
B. Hypophosphatemia
C. Hyperphosphatasia
D. Hyperparathyroidism

# Bone changs in hyperparathyroidism include :
A. Generalized demineralization
B. Brown Tumors
C. Cystic changes
D. All of the above

# Eosinophilic granuloma results from the proliferation of:
A. Histiocytes
B. Eosinophils
C. Lymphocytes
D. Fibroblast

# Acrodermatitis enteropathica is due to deficiency of:
A. Mercury
B. Zinc
C. Lead
D. Bismuth

# Vit D deficiency causes all except:
A. Widening of predentin
B. Defective calcification
C. Microdontia
D. Interglobular dentin formation

# An abnormal resorption pattern in primary teeth, delayed eruption of permanent teeth and a large tongue are the features of:
A. Addison's disease
B. Hypothyroidism
C. Hyperthyroidism
D. Von-Recklinghausen Disease

# Lamina dura is lost or partially lost in:
A. Hypothyroidism
B. Hyperthyroidism
C. Hypoparathyroidism
D. Hyperparathyroidism

# Which of the following is associated with a low concentration of ionized calcium in the serum ?
A. Hypothyroidism
B. Osteogenesis imperfecta
C. Paget's disease of the bone
D. Tetany # A 50 year old obese man complains of several recent abscesses in the gingiva with loosening of teeth. He also suffers from itching of the skin and polyuria. The most probable etiology is:
A. Scurvy
B. Myxoedema
C. Diabetes mellitus
D. Vitamin A Deficiency

# Giant cells are a characteristic histopathologic finding in:
A. Aphthous ulcers
B. Keratocyst
C. Brown Tumor of hyperparathyroidism
D. Dentigerous cyst

# Bone pain, bone cysts, fractures and renal stones are characteristics of:
A. Hyperparathyroidism
B. Cushing's syndrome
C. Multiple myeloma
D. Marfan's syndrome

# Beefy red and painful tongue is characteristic of:
A. Vitamin A deficiency
B. Any periodontal disease
C. Acute nicotinic acid deficiency
D. Ascorbic acid deficiency

# Letterer Siewe disease is a disturbance of:
A. Protein metabolism
B. Histiocytic disorder
C. Mucopolysaccharide metabolism
D. Carbohydrate metabolism

# Macrodontia is associated with:
A. Acromegaly
B. Pituitary gigantism
C. Hypoparathyroidism
D. Hyperthyrroidism

# Red fluorescent fluid is seen in:
A. Pemphigus
B. Erythema multiforme
C. Lichen Planus
D. Porphyria

# Hypogonadism, developmental delay, loss of taste and smell is due to deficiency of:
A. Cu
B. Zn
C. K
D. Cr

# Swollen joint, anemic, loose teeth and dentin dysplasia are because of deficiency of:
A. Vitamin C
B. Vitamin D
C. Vitamin B1
D. Vitamin E and D

# Intestinal absorption of calcium is decreased by:
A. Proteins
B. Lactose
C. Phytic acid
D. Acidity

# Brown tumors are seen in:
A. Hyperparathyroidism
B. Pigmented villonodular synovitis
C. Osteomalacia
D. Neurofibromatosis

# A 65 year old man is anemic, complains of back pain, has multiple radiolucencies in panoramic view. The diagnosis is:
A. Multiple Myeloma
B. Osteosarcoma
C. Giant cell granuloma
D. Eosinophilic

# Normal Serum calcium level is:
A. 5 to 7 mg %
B. 7 to 9 mg %
C. 9 to 11 mg %
D. 11 to 13 mg %

# Pigmentation occurs in oral cavity and skin in all of the following except:
A. Peutz-Jeghers Syndrome
B. Addison's Syndrome
C. Cushing's Syndrome
D. Albright Syndrome

# Radiological features seen in hyperparathyroidism are:
A. Loss of lamina dura
B. Osteitis fibrosa cystica
C. erosion below the duramater of skull
D. all of the above

# Which of the following vitamins is associated with manifestations of neurological problems ?
A. Vit A
B. Vit K
C. Folic Acid
D. Cyanocobalamine

# All of the following affects absorption of calcium, EXCEPT :
A. Citric acid
B. Retinoic acid
C. Phytates
D. Oxalates

# A 9 year old child has increased horizontal anterior bone loss, less cementum and on test shows excretion of phosphoethanolamine in urine. The child is suffering from:
A. Hypophosphatasia
B. Vit D resistant rickets
C. Juvenile periodontitis
D. Osteomalacia

# Which of the following may be a feature of Acromegaly?
A. Large tongue
B. Micrognathia
C. Hypoglycemia
D. Crowded teeth

# Wernicke's encephalopathy is caused by deficiency of:
A. Thiamine
B. Cyanocobalamine
C. Niacin
D. Riboflavin

# Hepatolenticular degeneration is seen with deposition of:
A. Cadmium
B. Lead
C. Aluminium
D. Copper

# Increase in height of mandible with increase in interdental spaces in elderly man:
A. Hyperpituitarism
B. Hyperthyroidism
C. Hypopituitarism
D. Hyperparathyroidism

# Reilly bodies are inclusion bodies seen in Hurler's syndrome within:
A. Lymphocytes
B. Fibroblast

# Hyperpigmentation is seen in all except:
A. Peutz Jeghers Syndrome
B. Addison's disease
C. Cushing's disease
D. Albright's syndrome

# A histologic evidence of widespreadd formation of globular hypocalcified dentin and pulp horns reaching the dentinoenamel junction, absence of lamina dura around the tooth in radiograph are the characteristic features of:
A. Vitamin D resistant rickets
B. Hypophosphatasia
C. Hypervitaminosis A
D. Vitamin A deficiency

# Addison's disease typically:
A. Causes Hypertension
B. Causes Hypopigmentation
C. Is an autoimmune disease
D. Steroids are contraindicated