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Polyene antibiotics exhibit their action on:

 # Polyene antibiotics exhibit their action on:
A. Cell membrane
B. Cell wall
C. Cell nucleus
D. Ribosomes



The correct answer is A. Cell Membrane.

Amphotericin, the polyenes antibiotics, have high affinity for ergosterol of fungal cell membranes to orient themselves to produce micropore through which ions, amino acids and water-soluble substances move out. It is not effective against bacteria as it does not contain sterol in their cell membrane. 

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