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Which of the following cytokeratin is not found in orthokeratinized epithelium?

 # Which of the following cytokeratin is not found in orthokeratinized epithelium?
A. K9
B. K10
C. K11
D. K19



The correct answer is D. K19

Keratins K1, K2, and K10 through K12, which are specific to epidermal-type differentiation, are immunohistochemically expressed with high intensity in orthokeratinized areas and with less intensity in parakeratinized areas. K6 and K16, which are characteristic of highly proliferative epithelia, and K5 and K14, which are stratification-specific cytokeratins, also are present. Parakeratinized areas express K19, which is usually absent from orthokeratinized normal epithelia.


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