Acute arthritis of the great (big) toe is a diagnostic sign

# Acute arthritis of the great (big) toe is a diagnostic sign of which of the following diseases?
A. Osteoarthritis
B. Osteomyelitis
C. Gout
D. Osteoporosis
E. Rheumatoid arthritis

The correct answer is C. Gout. 

The acute arthritis of the big toe is a

pathognomonic sign of Podagra or Gout.

What distinguishes Gout from others is that,

it usually occurs in one of the joints in the

body, however, about 50% are said to occur

in the big toe. This disease is also referred

to as "disease of the kings" or "the rich

man's disease".