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Paracetamol is contraindicated in:

# Paracetamol is contraindicated in:
A. Nephritis
B. Chronic hepatitis
C. Bleeding disorders
D. Pregnancy



The correct answer is B. Chronic Hepatitis. 

Most prominent toxic effect associated with acetaminophen use is hepatic necrosis. 
Paracetamol (Acetaminophen) has only analgesic and antipyretic action without any anti inflammatory action. Hypersensitivity reactions to paracetamol are rare and can be given to patients to whom aspirin is contraindicated. The most serious acute adverse effect of overdose of acetaminophen is a potentially fatal hepatic necrosis. Renal tubular necrosis and hypoglycemic coma may also occur. 

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